Karlsson was hurt blocking a shot in Tuesday's loss at Philadelphia and is questionable to play Thursday against Minnesota.
Analysis: The star defenseman didn't take part in Thursday's morning skate, so owners should have alternate plans in the event he's held out. Karlsson has played in 324 consecutive games, however, so chances are he'll be in the lineup if the injury isn't anything too concerning.
McDonagh missed Thursday's practice with an undisclosed injury, though the Rangers head coach Alain Vigneault said the team captain's status is "looking good" for Friday's game against Pittsburgh.
Analysis: McDonagh's injury doesn't appear to be a major concern, though there's certainly a chance the Rangers hold him out a game or two down the road with the team likely locked into the East's first wild card spot.
Hamilton scored the Flames' lone goal in Wednesday's loss to Los Angeles.
Analysis: The goal was Hamilton's 13th this season, a new career high for the upper-level fantasy defenseman. The 23-year-old has scored three times in his last eight games and recorded 10 points over a 12-game stretch in which he's a plus-10.
Elliott stopped just 29 of 33 shots in the Flames' loss to Los Angeles on Wednesday.
Analysis: Elliott hasn't had many subpar performances lately, as he entered the contest 13-1-0 with a 1.90 goals-against average and a .936 save percentage over his previous 14 starts. He'll likely get a chance to bounce back when the Flames host San Jose on Friday.
Gaudreau assisted on the Flames' lone goal in Wednesday's loss to Los Angeles to extend his point streak to six games.
Analysis: Calgary hasn't locked up a playoff spot just yet, but it will be a dangerous team if Gaudreau maintains his late-season pace. The dynamic forward has 10 points during the streak and 24 (six goals, 18 assists) through his last 18 contests. He's a plus-15 over the course of that stretch.
Carter ended his recent scoring slump by recording a late goal in Wednesday's win at Calgary.
Analysis: Just three of Carter's team-leading 32 goals have come during Los Angeles' last 21 games, and he entered Wednesday's matchup having gone a season-high eight straight without one. The Kings are 20-2-3 this season when Carter scores, so it would be a great boost to their sagging playoff hopes if he can get hot.
After being a healthy scratch in the Kings' previous game, Gaborik responded by recording two assists and finishing a plus-3 in Wednesday's win at Calgary.
Analysis: It's just the fourth time this season in which the three-time 40-goal scorer has had multiple points. Though his overall numbers have been disappointing, Gaborik could be a candidate for a late-year resurgence if he continues to play on a line with Anze Kopitar and Jarome Iginla.
Kopitar produced a goal and an assist while finishing a plus-3 in the Kings' 4-1 win at Calgary on Wednesday.
Analysis: Kopitar is doing his part to keep the Kings alive in the playoff chase, generating six goals and nine assists over his last 16 games. The Los Angeles captain has five multi-point outings during that time frame.
Playing perhaps for the final time in Calgary, Iginla scored in a second straight game and added an assist to help the Kings post an important 4-1 win over the Flames. The former Calgary captain also was involved in a fight and finished a plus-3.
Analysis: The in-season move to Los Angeles has boosted Iginla's numbers, as he's recorded five goals, two assists and 12 penalty minutes over his last 11 games to put himself back into the fantasy conversation.
Johansson scored a power-play goal on his only shot Wednesday and added an assist in a win at Colorado.
Analysis: Johansson has eight points in his last four games, and there's no reason to think he'll slow down. Washington has three stops left on a five-game trip, and Johansson has four goals and eight assists in his last seven road games. He has only two points in his last nine at home.
Fleury surrendered five goals - four in the first period - on 36 shots in Wednesday's loss to Chicago.
Analysis: The poor start resulted in the veteran's third loss in four starts, with Fleury allowing three or more goals in each of those defeats. Matt Murray isn't playing particularly well right now either, so the two could continue to work in a tandem until one gets hot.